The most common and most likely answer to this crossword clue is the 2 plus 3 plus 2 plus 1 plus 6 letter word AS MAD AS A HATTER
A
S
M
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D
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H
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More clues leading to the result AS MAD AS A HATTER
Buddy explains!

The straight part
We know that "going round the bend/s" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case going round the bend/s = as mad as a hatter.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.