Cryptic crossword clue
Second piece of peel came down twisted 8

The most common and most likely answer to this crossword clue is the 8 letter word SPRAINED

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The straight part
We know that "twisted" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case twisted = sprained.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SPRAINED mean?

SPRAINED verb
  1. To weaken, as a joint, ligament, or muscle, by sudden and excessive exertion, as by wrenching; to overstrain, or stretch injuriously, but without luxation

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