The most common and most likely answer to this crossword clue is the 8 letter word SEASCAPE
S
E
A
S
C
A
P
E
More clues leading to the result SEASCAPE
- Small key locking in a painting
- The main picture?
- See about a second better work of art
- Cover used in small facility’s main view
- Safe’s opening before key secures a painting
- Protective cover on sides of settee when painting
- Main work of an artist
- Special issue encapsulates a boating image?
- Visualise frames as better for painting
- Watercolour?
Buddy explains!

The straight part
We know that "work of art" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case work of art = seascape.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does SEASCAPE mean?
SEASCAPE noun- A piece of art that depicts the sea or shoreline.