The most common and most likely answer to this crossword clue is the 6 letter word EASILY
I've seen this crossword clue in The Guardian
E
A
S
I
L
Y
More clues leading to the result EASILY
- Undoubtedly like one to visit cathedral city
- English like the Italian boy ultimately without difficulty
- Simply sail off in case of emergency
- Each nincompoop losing heart in an uncomplicated manner
- Article is elevated in cathedral without difficulty
- Very probably see round Aussie now and then
- . Casually spinning lie, say
- See about set-up of ISA with no trouble
- Sailing through they half trimmed round flapping sail
- Midshipman drinks one litre, no problem
Buddy explains!

The straight part
We know that "with no trouble" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case with no trouble = easily.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does EASILY mean?
EASILY adverb- Comfortably, without discomfort or anxiety.
- Without difficulty.
- Absolutely, without question.