Cryptic crossword clue
   Selfish endeavour say to put up inscription on tomb 3,4

The most common and most likely answer to this crossword clue is the 3 plus 4 letter word EGO TRIP

I've seen this crossword clue in Independent
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The straight part
We know that "Selfish endeavour" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case selfish endeavour = ego trip.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does EGO TRIP mean?

EGO TRIP verb
  1. To go on an ego trip; to behave in such a manner.

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