Cryptic crossword clue
Sense of hopelessness at getting lost in analysis 5

The most common and most likely answer to this crossword clue is the 5 letter word ANOMY

A
N
O
M
Y

Buddy explains!

The straight part
We know that "Sense of hopelessness" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case sense of hopelessness = anomy.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ANOMY mean?

ANOMY noun
  1. Alienation or social instability caused by erosion of standards and values.

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