Cryptic crossword clue
Separate European city located in the 23? 5,2

The most common and most likely answer to this crossword clue is the 5 plus 2 letter word SPLIT UP

I've seen this crossword clue in The Daily Telegraph
S
P
L
I
T
U
P


Buddy explains!

The straight part
We know that "Separate" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case separate = split up.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SPLIT UP mean?

SPLIT UP noun
  1. A break-up.

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