Cryptic crossword clue
Series of comments about keeping a number of commandments? 6

The most common and most likely answer to this crossword clue is the 6 letter word CATENA

I've seen this crossword clue in The Times
C
A
T
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N
A


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The straight part
We know that "Series of comments" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case series of comments = catena.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does CATENA mean?

CATENA noun
  1. A series of related items.
  2. A series of distinct soils arrayed along a slope.

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