Cryptic crossword clue
Series of six having ten in front 5

The most common and most likely answer to this crossword clue is the 5 letter word HEXAD

I've seen this crossword clue in Financial Times
H
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The straight part
We know that "Series of six" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case series of six = hexad.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does HEXAD mean?

HEXAD noun
  1. A group of six.
  2. An element or radical with the combining power of six units, i.e. six atoms of hydrogen.

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