Cryptic crossword clue
Serious honour senior accepts 5

The most common and most likely answer to this crossword clue is the 5 letter word SOBER

I've seen this crossword clue in The Times
S
O
B
E
R


Buddy explains!

The straight part
We know that "Serious" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case serious = sober.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SOBER mean?

SOBER verb
  1. (often with up) To make or become sober.
  2. (often with up) To overcome or lose a state of intoxication.
  3. To moderate one's feelings
SOBER adjective
  1. Not drunk; not intoxicated
  2. Not given to excessive drinking of alcohol
  3. Moderate; realistic; serious; not playful; not passionate; cool; self-controlled
  4. Dull; not bright or colorful
  5. Subdued; solemn; grave
  6. Poor; feeble

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