Cryptic crossword clue
Serious to lose wicket, having score less than 100 6

The most common and most likely answer to this crossword clue is the 6 letter word EIGHTY

I've seen this crossword clue in Financial Times
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Buddy explains!

The straight part
We know that "score less than 100" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case score less than 100 = eighty.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does EIGHTY mean?

EIGHTY numeral
  1. The cardinal number occurring after seventy-nine and before eighty-one, represented in Roman numerals as LXXX and in Arabic numerals as 80.

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