Cryptic crossword clue
Set on answer held by one setting off 9

The most common and most likely answer to this crossword clue is the 9 letter word INSTIGATE

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
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What does INSTIGATE mean?

INSTIGATE verb
  1. To incite; to bring about by urging or encouraging
  2. To goad or urge (a person) forward, especially to wicked actions; to provoke

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