Cryptic crossword clue
Sets of animals go off, one perhaps on horse 10

The most common and most likely answer to this crossword clue is the 10 letter word PACKSADDLE

I've seen this crossword clue in The Times
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The straight part
We know that "one perhaps on horse" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case one perhaps on horse = packsaddle.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does PACKSADDLE mean?

PACKSADDLE noun
  1. A saddle designed to secure and carry goods on the back of an animal.

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