The most common and most likely answer to this crossword clue is the 5 letter word MIAMI
I've seen this crossword clue in The Guardian
M
I
A
M
I
More clues leading to the result MIAMI
- Note repeated about a city in Florida
- Note copied about a city
- Seriously wound up one in US resort
- City revolutionary the writer cripples?
- I damage upcoming resort
- I may initially end up in US resort
- I wound up in US resort
- End up north of Michigan in US city
- Motorways orbiting a city abroad
- Recollection of lame setter in US resort
Buddy explains!
The straight part
We know that "city once associated with vice" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case city once associated with vice = miami.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.