The most common and most likely answer to this crossword clue is the 6 letter word VIAGRA
I've seen this crossword clue in Independent
V
I
A
G
R
A
More clues leading to the result VIAGRA
- Promoter of the other version of Sex & The City?
- This promotes erection of fancy vicarage, not church
- Drug — the classical way to swallow a grain
- Good artist following through with drug
- Sex aid? A person who’s worn out has six!
- Something to revive libido by way of innate character dropping in
- This’ll make you an upstanding member in the Netherlands, perhaps?
- Sixth Indian city supplying aid to union
- In Scandinavia grandpa discovered
- Drug passing through elderly relative, a bit lost
Buddy explains!
The straight part
We know that "it has one staying up" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case it has one staying up = viagra.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does VIAGRA mean?
VIAGRA noun- Alternative form of Viagra