The most common and most likely answer to this crossword clue is the 4 letter word FAZE
F
A
Z
E
More clues leading to the result FAZE
- Worry as distinct period of change announced
- Sound from stage floor
- Disturb fairies, by the sound of it
- Upset produced by iron-bound extremist characters
- Shake stage when speaking
- Aspect of moon’s appearance said to unsettle
- Disturb state broadcast
- Shake stage for audience
- Put on the spot in a jungle? Change sex
Buddy explains!

The straight part
We know that "Shake" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case shake = faze.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does FAZE mean?
FAZE verb- To frighten or cause hesitation; to daunt, put off (usually used in the negative); to disconcert, to perturb.