Cryptic crossword clue
Shake-up by police once code- breaker mathematician goes on holiday? 13

The most common and most likely answer to this crossword clue is the 13 letter word RESTRUCTURING

I've seen this crossword clue in Financial Times
R
E
S
T
R
U
C
T
U
R
I
N
G

Buddy explains!

The straight part
We know that "Shake-up/3" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case shake-up/3 = restructuring.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does RESTRUCTURING mean?

RESTRUCTURING verb
  1. To change the organization of.
  2. To modify the terms of a loan, providing relief to a debtor who would otherwise be forced to default.
RESTRUCTURING noun
  1. A reorganization; an alteration of structure.

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