The most common and most likely answer to this crossword clue is the 8 letter word ISABELLA
I've seen this crossword clue in The Guardian
I
S
A
B
E
L
L
A
More clues leading to the result ISABELLA
- One's label confused a girl
- Girl showing alarm in Asia when in trouble
- Spanish queen, the first murder victim in one's city?
- Female murder victim to be buried in Scottish island shortly
- Allies in a tizzy about sailor's girl
- Spanish ruler’s second son into religion briefly
- Girl libels AA organisation
- She jointly made Columbus sail and able to roam
- Religion endlessly engrossing murder victim’s girl
- Queen mixes Asia up, entertaining clanger!
Buddy explains!

The straight part
We know that "She jointly made Columbus sail and able to roam" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case she jointly made columbus sail and able to roam = isabella.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does ISABELLA mean?
ISABELLA noun- A pale grey-yellow, fawn, cream-brown or parchment colour.