The most common and most likely answer to this crossword clue is the 6 letter word SLOUGH
I've seen this crossword clue in Financial Times
S
L
O
U
G
H
More clues leading to the result SLOUGH
- Stagnant swamp in Berkshire town
- Swamp primarily surrounding Irish lake
- Shed somewhere in Berkshire
- Discard top of swimsuit? See, that’s disgusting!
- Bog in shed
- Left to look into moaning sound coming from shed
- Cast off in southern Irish lake
- Shed in Berkshire town
- Small lake in Berkshire town
- Southern water where friendly bombs were wanted
Buddy explains!

The straight part
We know that "Shed/Berkshire town" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case shed/berkshire town = slough.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does SLOUGH mean?
SLOUGH noun- The skin shed by a snake or other reptile.
- Dead skin on a sore or ulcer.
- To shed (skin).
- To slide off (like a layer of skin).
- To discard.
- (Western US) To commit truancy, be absent from school without permission. (compare ditch)
- A muddy or marshy area.
- (Eastern United States) A type of swamp or shallow lake system, typically formed as or by the backwater of a larger waterway, similar to a bayou with trees.
- (Western United States) A secondary channel of a river delta, usually flushed by the tide.
- A state of depression.
- A small pond, often alkaline, many but not all formed by glacial potholes.