Cryptic crossword clue
Sheep in main road is right little madam 6

The most common and most likely answer to this crossword clue is the 6 letter word ARGALI

I've seen this crossword clue in The Guardian
A
R
G
A
L
I

Buddy explains!

The straight part
We know that "Sheep" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case sheep = argali.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ARGALI mean?

ARGALI noun
  1. Ovis ammon, the largest wild sheep, which roams the highlands of Central Asia.

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