The most common and most likely answer to this crossword clue is the 7 letter word SEDATED
I've seen this crossword clue in Independent
S
E
D
A
T
E
D
More clues leading to the result SEDATED
- She regularly went out and used drugs
- Starts to smoke, eventually saw someone tranquillised
- Made calm case, not half old-fashioned
- Son had an online affair, then chilled with drugs
- Out to an extent in chair round Land’s End
- Made calm declaration initially during sitting
- Shortened see saw soothed
- Seem dead trendy, oddly, though drugged
- Soothed by unending see saw
- Under the influence of drugs, dead set to party
Buddy explains!

The straight part
We know that "soothed" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case soothed = sedated.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does SEDATED mean?
SEDATED verb- To calm or put (a person) to sleep using a sedative drug.
- To make tranquil.