The most common and most likely answer to this crossword clue is the 8 letter word NAUSEOUS
I've seen this crossword clue in The Daily Telegraph
N
A
U
S
E
O
U
S
More clues leading to the result NAUSEOUS
- A purpose in mind, disgusting
- Feeling unwell about employment? Show some sense about that
- Abroad, we adopt a custom poorly
- Sickening talent – active exercise limited
- Sick, showing common sense without a purpose
- It’s common sense there’s a purpose in feeling sick
- Strike season — unions under the weather
- A druggie, ultimately lacking in sense, about to retch?
Buddy explains!
The straight part
We know that "Sick" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case sick = nauseous.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does NAUSEOUS mean?
NAUSEOUS adjective- Causing nausea; sickening or disgusting.
- (sometimes proscribed) Afflicted with nausea; sick.