Cryptic crossword clue
Sign for esoteric sectarian 10

The most common and most likely answer to this crossword clue is the 10 letter word PROGNOSTIC

I've seen this crossword clue in The Times
P
R
O
G
N
O
S
T
I
C

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The straight part
We know that "Sign" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case sign = prognostic.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does PROGNOSTIC mean?

PROGNOSTIC noun
  1. Prognosis
  2. A sign by which a future event may be known or foretold.
  3. A prediction of the future.
  4. One who predicts the future.
PROGNOSTIC adjective
  1. Of, pertaining to or characterized by prognosis or prediction.

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