Cryptic crossword clue
Sign that Tommy’s upset about Penny 7

The most common and most likely answer to this crossword clue is the 7 letter word SYMPTOM

I've seen this crossword clue in The Guardian
S
Y
M
P
T
O
M


Buddy explains!

The straight part
We know that "Sign" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case sign = symptom.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SYMPTOM mean?

SYMPTOM noun
  1. A perceived change in some function, sensation or appearance of a person that indicates a disease or disorder, such as fever, headache or rash.
  2. A signal; anything that indicates, or is characteristic of, the presence of something else, especially of something undesirable.

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