Cryptic crossword clue
Significance of less than wholesome wine 7

The most common and most likely answer to this crossword clue is the 7 letter word PURPORT

P
U
R
P
O
R
T

Buddy explains!

The straight part
We know that "Significance of" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case significance of = purport.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does PURPORT mean?

PURPORT noun
  1. Import, intention or purpose
  2. Disguise; covering
PURPORT verb
  1. To convey, imply, or profess outwardly (often falsely).
  2. (construed with to) To intend.

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