The most common and most likely answer to this crossword clue is the 5 letter word OMAGH
O
M
A
G
H
More clues leading to the result OMAGH
- Surprised reaction about publication in market town
- County town publication placed in old hospital
- Ulster town’s old periodical
- Surprised comment about publication in Irish town
- Surprised response about publication from town in Northern Ireland
- Significant order taken by a good hotel in Northern Irish town
- HO AGM organised in town near Belfast
- Some from a ghost town in Tyrone
Buddy explains!

The straight part
We know that "Northern Irish town" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case northern irish town = omagh.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.