Cryptic crossword clue
Sinful desire getting endurance athletes high in a natural way? 15

The most common and most likely answer to this crossword clue is the 15 letter word ENVIRONMENTALLY

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Buddy explains!

The straight part
We know that "in a natural way" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case in a natural way = environmentally.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ENVIRONMENTALLY mean?

ENVIRONMENTALLY adverb
  1. In a manner affecting the environment.

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