Cryptic crossword clue
Singular excrescence, malignant 5

The most common and most likely answer to this crossword clue is the 5 letter word SWART

S
W
A
R
T

Buddy explains!

The straight part
We know that "malignant" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case malignant = swart.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SWART mean?

SWART noun
  1. Black or dark dyestuff; something of a certain swart; something of a certain ocker.
SWART adjective
  1. Of a dark hue; moderately black; swarthy; tawny.
  2. Black.
  3. Gloomy; malignant.
SWART verb
  1. To make swart or tawny; blacken; tan.
SWART noun
  1. A layer of earth into which grass has grown; turf; sod.
  2. An expanse of land covered in grass; a lawn or meadow.
  3. Skin; covering.

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