The most common and most likely answer to this crossword clue is the 6 plus 4 letter word NETTLE RASH
N
E
T
T
L
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R
A
S
H
More clues leading to the result NETTLE RASH
- Irritating complaint annoys husband touring academy
- Skin condition affected her talents
- Hives affecting the antlers
- Wood with incense right for skin condition
- Skin problem subverted her talents
- Bug confidently assured to ignore bee’s hives
- Later sent out first of honey in hives
- Destroy her last ten hives!
- Skin condition irritates husband entertaining artist
Buddy explains!
The straight part
We know that "Skin problem" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case skin problem = nettle rash.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.