The most common and most likely answer to this crossword clue is the 5 letter word CLONE
C
L
O
N
E
More clues leading to the result CLONE
- Caught, having left company, making illegal copy
- Certificate, initially single copy
- Tory holds Liberal ultimately responsible for hacked phone
- Copy line seen in feature of roadworks
- Small amount of liquid I spit
- Not an original individual about to get detached from others
- Line complete following carbon copy
- Separate after carbon copy
- . Cc. to a biologist?
- Even in scale, an exact replica
Buddy explains!

The straight part
We know that "spit" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case spit = clone.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does CLONE mean?
CLONE noun- A living organism (originally a plant) produced asexually from a single ancestor, to which it is genetically identical.
- A group of identical cells derived from a single cell.http//www.medterms.com/script/main/art.asp?articlekey=2754
- A copy or imitation of something already existing, especially when designed to simulate it.
- Two people who are exactly alike, as far as looks or behavior.
- To create a clone of.