The most common and most likely answer to this crossword clue is the 5 letter word STOMA
I've seen this crossword clue in The Times
S
T
O
M
A
More clues leading to the result STOMA
- Opening of a test's beginning at the southern end
- Opening line forgotten, almost disastrously
- Somewhat serious to make a surgical opening
- Small opening allows last couple to escape bear
- Artificial opening for most of the corporation
- Essential for process to manufacture tiny things
- Opening boy’s found in army
- Opening for cat in South America
- Vibrating atom's hole
- Small cat has a mouth, perhaps
Buddy explains!
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does STOMA mean?
STOMA noun- One of the tiny pores in the epidermis of a leaf or stem through which gases and water vapor pass.
- A small opening in a membrane; a surgically constructed opening, especially one in the abdominal wall that permits the passage of waste after a colostomy or ileostomy.
- A mouthlike opening, such as the oral cavity of a nematode.
- An artificial anus.