The most common and most likely answer to this crossword clue is the 7 letter word DEFAMED
I've seen this crossword clue in The Guardian
D
E
F
A
M
E
D
Buddy explains!
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does DEFAMED mean?
DEFAMED verb- To disgrace; to bring into disrepute.
- To charge; to accuse (someone) of an offence.
- To harm or diminish the reputation of; to disparage.