The most common and most likely answer to this crossword clue is the 6 letter word ALEPPO
A
L
E
P
P
O
More clues leading to the result ALEPPO
- Drink very quietly with opposition leader in Syria
- Drink fizzy pop in Levantine city
- Maybe bitter uprising works in war-torn city
- Drink exotic pop in Syria
- Drink fizzy pop in ancient city
- Pop out after beer in Syrian city
- A 3 about double parking in Syrian city
- ‘Softly, softly’ lion’s caged, under a Syrian city
- Drink disgusting pop in Syrian city
- Gangster and comic brother head off for place in the Middle- East
Buddy explains!

The straight part
We know that "Syrian city" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case syrian city = aleppo.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.