The most common and most likely answer to this crossword clue is the 5 letter word ELIZA
E
L
I
Z
A
More clues leading to the result ELIZA
- Some lounge lizard’s girl
- Back in Brazil, educating professor’s pupil
- Girl entrapped by lounge lizard
- Woman priest getting the support of South Africa
- Female slave in South Africa overlooked by priest
- Wager husband will leave queen for dramatic social climber
- Henry’s protege having Tudor name, up to a point
Buddy explains!

The straight part
We know that "girl" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case girl = eliza.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.