Cryptic crossword clue
Some prefer Michael to Enrico, perhaps 5

The most common and most likely answer to this crossword clue is the 5 letter word FERMI

F
E
R
M
I


Buddy explains!

The straight part
We know that "Enrico, perhaps" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case enrico, perhaps = fermi.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does FERMI mean?

FERMI noun
  1. An obsolete unit of length equal to one femtometer or femtometre (10−15 m).

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