Cryptic crossword clue
Something fishy about sister with unusual problem 9

The most common and most likely answer to this crossword clue is the 9 letter word CONUNDRUM

I've seen this crossword clue in The Times
C
O
N
U
N
D
R
U
M


Buddy explains!

The straight part
We know that "problem" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case problem = conundrum.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does CONUNDRUM mean?

CONUNDRUM noun
  1. A difficult question or riddle, especially one using a play on words in the answer.
  2. A difficult choice or decision that must be made.

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