The most common and most likely answer to this crossword clue is the 10 letter word PROFUNDITY
I've seen this crossword clue in The Sunday Telegraph
P
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O
F
U
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More clues leading to the result PROFUNDITY
Buddy explains!

The straight part
We know that "Something insightful said" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case something insightful said = profundity.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does PROFUNDITY mean?
PROFUNDITY noun- The state of being profound or abstruse.
- A great depth.
- Deep intellect or insight.