Cryptic crossword clue
Something to brush up on taking answer for one down 5

The most common and most likely answer to this crossword clue is the 5 letter word QUAFF

Q
U
A
F
F

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The straight part
We know that "down" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case down = quaff.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does QUAFF mean?

QUAFF noun
  1. The act of quaffing; a deep draught.
QUAFF verb
  1. To drink or imbibe with vigour or relish; to drink copiously; to swallow in large draughts.

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