Cryptic crossword clue
Soothing remedy never working, popular for swallowing 7

The most common and most likely answer to this crossword clue is the 7 letter word NERVINE

I've seen this crossword clue in The Guardian
N
E
R
V
I
N
E

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does NERVINE mean?

NERVINE noun
  1. A drug or substance that acts upon the nerves.
NERVINE adjective
  1. Having the quality of acting upon or affecting the nerves; quieting nervous excitement.

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