The most common and most likely answer to this crossword clue is the 6 letter word CANKER
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The straight part
We know that "sore" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case sore = canker.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does CANKER mean?
CANKER noun- A plant disease marked by gradual decay.
- A region of dead plant tissue caused by such a disease.
- A worm or grub that destroys plant buds or leaves; cankerworm.
- A corroding or sloughing ulcer; especially a spreading gangrenous ulcer or collection of ulcers in or about the mouth.
- Anything which corrodes, corrupts, or destroys.
- A kind of wild rose; the dog rose.
- An obstinate and often incurable disease of a horse's foot, characterized by separation of the horny portion and the development of fungoid growths. Usually resulting from neglected thrush.
- An avian disease affecting doves, poultry, parrots and birds of prey, caused by Trichomonas gallinae.
- To affect as a canker; to eat away; to corrode; to consume.
- To infect or pollute; to corrupt.
- To waste away, grow rusty, or be oxidized, as a mineral.
- To be or become diseased, or as if diseased, with canker; to grow corrupt; to become venomous.