Cryptic crossword clue
South American maidens besieged famous Red Indian chiefs 7

The most common and most likely answer to this crossword clue is the 7 letter word SACHEMS

S
A
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S

Buddy explains!

The straight part
We know that "Indian chiefs" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case indian chiefs = sachems.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SACHEMS mean?

SACHEMS noun
  1. The chief of a Native American tribe; a sagamore.
  2. A leader in the Tammany Hall society.

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