Cryptic crossword clue
Spleen on being spurned by poet 4

The most common and most likely answer to this crossword clue is the 4 letter word MILT

M
I
L
T

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MILT mean?

MILT noun
  1. The spleen, especially of an animal bred for food.
  2. The semen of a male fish.
MILT verb
  1. To impregnate (the roe of a fish) with milt.

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