Cryptic crossword clue
Spoke quietly to relative, terminally ill in bed

The most common and most likely answer to this crossword clue is the 7 letter word MUMBLED

I've seen this crossword clue in The Guardian
M
U
M
B
L
E
D

Buddy explains!

The straight part
We know that "Spoke quietly" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case spoke quietly = mumbled.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MUMBLED mean?

MUMBLED verb
  1. To speak unintelligibly or inaudibly; to fail to articulate.
  2. To chew something gently with closed lips.

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