Cryptic crossword clue
Spot a complicated clue — but it’s of little matter 8

The most common and most likely answer to this crossword clue is the 8 letter word MOLECULE

I've seen this crossword clue in The Daily Telegraph
M
O
L
E
C
U
L
E


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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MOLECULE mean?

MOLECULE noun
  1. The smallest particle of a specific element or compound that retains the chemical properties of that element or compound; two or more atoms held together by chemical bonds.
  2. A tiny amount.

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