The most common and most likely answer to this crossword clue is the 5 letter word POINT
P
O
I
N
T
More clues leading to the result POINT
Buddy explains!

The straight part
We know that "Spot" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case spot = point.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does POINT mean?
POINT noun- A discrete division of something.
- A sharp extremity.
- One of the several different parts of the escutcheon.
- A short piece of cordage used in reefing sails.
- A string or lace used to tie together certain garments.
- Lace worked by the needle.
- An item of private information; a hint; a tip; a pointer.
- The attitude assumed by a pointer dog when he finds game.
- The perpendicular rising of a hawk over the place where its prey has gone into cover.
- The act of pointing, as of the foot downward in certain dance positions.
- The gesture of extending the index finger in a direction in order to indicate something.
- A vaccine point.
- In various sports, a position of a certain player, or, by extension, the player occupying that position.
- To extend the index finger in the direction of something in order to show where it is or to draw attention to it.
- To draw attention to something or indicate a direction.
- To face in a particular direction.
- (sometimes figurative) To direct toward an object; to aim.
- To give a point to; to sharpen; to cut, forge, grind, or file to an acute end.
- To indicate a probability of something.
- To repair mortar.
- To fill up and finish the joints of (a wall), by introducing additional cement or mortar, and bringing it to a smooth surface.
- (stone-cutting) To cut, as a surface, with a pointed tool.
- To direct or encourage (someone) in a particular direction.
- To separate an integer from a decimal with a decimal point.
- To mark with diacritics.
- To supply with punctuation marks; to punctuate.
- To direct the central processing unit to seek information at a certain location in memory.
- To direct requests sent to a domain name to the IP address corresponding to that domain name.
- To sail close to the wind.
- To indicate the presence of game by a fixed and steady look, as certain hunting dogs do.
- (of an abscess) To approximate to the surface; to head.
- To give point to (something said or done); to give particular prominence or force to.
- To appoint.