The most common and most likely answer to this crossword clue is the 7 letter word BLOTCHY
I've seen this crossword clue in The Guardian
B
L
O
T
C
H
Y
Buddy explains!

The straight part
We know that "Spotted" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case spotted = blotchy.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does BLOTCHY mean?
BLOTCHY adjective- Covered in blotches.