Cryptic crossword clue
Spotty youth once slated wrongly 10

The most common and most likely answer to this crossword clue is the 10 letter word ADOLESCENT

I've seen this crossword clue in Financial Times
A
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Buddy explains!

The straight part
We know that "Spotty youth" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case spotty youth = adolescent.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ADOLESCENT mean?

ADOLESCENT noun
  1. A person who is in adolescence; someone who has reached puberty but is not yet an adult.
ADOLESCENT adjective
  1. Of, relating to, or at the age of adolescence; at the stage between being a child and an adult

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