The most common and most likely answer to this crossword clue is the 7 letter word WRITHES
W
R
I
T
H
E
S
Buddy explains!
The straight part
We know that "Squirms" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case squirms = writhes.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does WRITHES mean?
WRITHES noun- A contortion.
- (knot theory) The number of negative crossings subtracted from the number of positive crossings in a knot
- To twist, to wring (something).
- To contort (a part of the body).
- To twist or contort the body; to be distorted.
- To extort.