Cryptic crossword clue
Stack Beano at first with earlier back issue 7

The most common and most likely answer to this crossword clue is the 7 letter word LUMBAGO

I've seen this crossword clue in The Guardian
L
U
M
B
A
G
O


Buddy explains!

The straight part
We know that "back issue" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case back issue = lumbago.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does LUMBAGO mean?

LUMBAGO noun
  1. Backache of the lumbar region or lower back, which can be caused by muscle strain or a slipped disk.

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