Cryptic crossword clue
Start to play with new protein 5

The most common and most likely answer to this crossword clue is the 5 letter word ACTIN

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Buddy explains!

The straight part
We know that "protein" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case protein = actin.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ACTIN mean?

ACTIN noun
  1. A globular structural protein that polymerizes in a helical fashion to form an actin filament (or microfilament).
  2. One of the six isoforms of actin.

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